Table 1.

Comparison of locomotor activities obtained before and after social defeat stress among three groups

Parameters	Control group (n = 15)			p a	Unsusceptible group (n = 20–21)			p a	Susceptible group (n = 38–39)			p a	p b
	Before	After	Change		Before	After	Change		Before	After	Change
Distance travelled (cm)	10,265.16 ± 813.84	9520.58 ± 635.32	− 593.49 ± 812.32	0.401	9416.40 ± 565.47	7138.97 ± 483.44	− 1457.57 ± 617.62	0.001	9082.38 ± 296.26	8313.24 ± 292.81	− 629.96 ± 317.99	0.018	0.431
Time spent in central zone (25%)	83.87 ± 17.63	27.24 ± 4.96	− 49.88 ± 9.92	0.004	104.49 ± 15.02	51.70 ± 7.66	− 57.66 ± 13.48	0.002	103.65 ± 11.94	28.54 ± 5.23	− 67.35 ± 7.88	< 0.001	0.494
Time spent in central zone (50%)	357.77 ± 65.91	158.46 ± 31.14	− 154.02 ± 33.75	0.008	335.34 ± 36.32	134.81 ± 24.06	− 177.15 ± 33.68	< 0.001	296.35 ± 30.94	152.84 ± 20.38	− 125.55 ± 25.92	< 0.001	0.449
Locomotion time (sec)	1205.35 ± 78.34	1121.15 ± 62.03	− 41.86 ± 65.94	0.347	1138.77 ± 56.74	841.68 ± 65.19	− 330.28 ± 59.17*†	< 0.001	1123.74 ± 33.28	1038.77 ± 29.33	− 116.99 ± 32.72	0.026	0.001

Data expressed as mean ± S.E.M

^aStudent’s paired t test between the data obtained before and after social defeat stress

^bOne-way ANOVA for the change

* p < 0.05 versus susceptible group

^†p < 0.05 versus control group