Table 4.
Western blot results of intracellular trafficking related proteins (ARF-6, GASP-1, Rab4 and Rab11) among three groups
| Brain regions | Control group (n = 7–9) | Unsusceptible group (n = 7–10) | Susceptible group (n = 16–19) | p | |
|---|---|---|---|---|---|
| ARF-6 | PFC | 1 ± 0.13 | 0.87 ± 0.12 | 0.99 ± 0.04 | 0.552 |
| ST | 1 ± 0.12 | 1.15 ± 0.03 | 0.95 ± 0.08 | 0.371 | |
| AMY | 1 ± 0.09 | 1.37 ± 0.09 | 1.20 ± 0.08 | 0.094 | |
| HIP | 1 ± 0.12 | 0.95 ± 0.11 | 1.06 ± 0.07 | 0.691 | |
| GASP-1 | PFC | 1 ± 0.13 | 1.31 ± 0.19 | 0.91 ± 0.06 | 0.054 |
| ST | 1 ± 0.14 | 0.89 ± 0.07 | 0.94 ± 0.05 | 0.249 | |
| AMY | 1 ± 0.10 | 1.33 ± 0.12 | 1.32 ± 0.06* | 0.043 | |
| HIP | 1 ± 0.10 | 1.24 ± 0.13 | 0.98 ± 0.06 | 0.123 | |
| Rab4 | PFC | 1 ± 0.07 | 1.20 ± 0.14 | 1.30 ± 1.10 | 0.276 |
| ST | 1 ± 0.11 | 1.04 ± 0.16 | 1.08 ± 0.06 | 0.944 | |
| AMY | 1 ± 0.07 | 1.17 ± 0.06 | 1.27 ± 0.04* | 0.005 | |
| HIP | 1 ± 0.11 | 1.04 ± 0.09 | 0.88 ± 0.04 | 0.303 | |
| Rab11 | PFC | 1 ± 0.06 | 1.17 ± 0.08 | 1.21 ± 0.04 | 0.097 |
| ST | 1 ± 0.12 | 1.22 ± 0.05 | 1.17 ± 0.06 | 0.204 | |
| AMY | 1 ± 0.10 | 1.07 ± 0.09 | 1.07 ± 0.04 | 0.742 | |
| HIP | 1 ± 0.13 | 1.20 ± 0.09 | 1.21 ± 0.04 | 0.185 |
Data were expressed in mean ± S.E.M
ARF-6 ADP-ribosylation factor 6, GASP-1 GPCR associated sorting protein-1
* p < 0.05 versus control group