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. 2018 Sep 17;115(40):9998–10003. doi: 10.1073/pnas.1812256115

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Copyright © 2018 the Author(s). Published by PNAS.

This open access article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND).

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Fig. 4. — Detailed interactions between Cdc73 and Ctr9, as well as between Cdc73 and Paf1 in the mtPAF1 complex. (A) Schematic representation of the interactions between Cdc73 and Ctr9, as well as between Cdc73 and Paf1. (B) Cdc73 α1 and its flanking loop interact with both Ctr9 and Paf1. (C) Detailed interactions between Cdc73 α2 and its flanking loops with Ctr9. (D) Interactions between Cdc73 α3 and Ctr9. (E) In vitro reconstitution of MBP-tagged Cdc73(155-227) or its mutants with the binary complex of Ctr9(31-967)-Paf1(1-120).