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Timeline of the experimental design. Thirty days after receiving AEA (100 ng) and/or STZ (2 mg/kg), rats were submitted to behavioral tasks to detect early deficits of emotional and non-emotional memories and sensorimotor gating. One week after the end of behavioral tasks, the animals were sacrificed for either neurochemical analysis of their hippocampi by Western Blotting (WB) or histological analyses of their brains.
