. Author manuscript; available in PMC: 2019 Jul 12.

Published in final edited form as: J Med Chem. 2018 Jun 25;61(13):5679–5691. doi: 10.1021/acs.jmedchem.8b00641

Table 4.

Antifungal Activity of VNI and Derivatives (MIC ± SEM, μg/mL)

A fumigatus strain	VNI	1	p- value	2	p- value	3	p- value	15	p- value
1022	0.48 ± 0.05	0.29 ± 0.03	0.0001^a	0.19 ± 0.03	0.0003^a	0.19 ± 0.03	0.0002^a	0.48 ± 0.05	1
32820	0.08 ± 0.03	0.08 ± 0.03	0.0009^a	0.09 ± 0.02	0.0027^a	0.06 ± 0.01	0.0004^a	0.19 ± 0.03	0.21
MYA-3626	0.08 ± 0.03	0.78 ± 0.03	0.0035^a	0.39 ± 0.05	0.0001^a	0.39 ± 0.05	0.0001^a	0.78 ± 0.04	0.0035^a

Statistically significant differences; p−values were analyzed by one-way ANOVA.