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. 2018 Oct 2;9:826. doi: 10.3389/fneur.2018.00826

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Copyright © 2018 Cheng, Cortese, Monti, Wang, Riganello, Arcuri, Di and Schnakers.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Brain areas with treatment-related metabolic changes. The left side of (A) illustrates, at the group level, areas with treatment-related metabolic changes which include the right middle frontal gyrus, the right superior temporal gyrus as well as the bilateral ventro-anterior thalamic nucleus (L = left, R = right) (p < 0.005 voxel-wise uncorrected). On the right side of (A), z-scores for each activated area are also reported at each phase (ABAB) for patients MCS 7, MCS 8, and VS 11. (B) Shows the CRS-R total scores on the last week of each phase (ABAB) for patients MCS 7, MCS 8, and VS 11.