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Heatmap of tumor voxel clusters that were significantly associated with the presence of IDH mutations in the glioblastoma (upper panel) and lower-grade glioma cohort (lower panel). Voxel-wise threshold of P < 0.05 based on a permutation test (n = 1000 iterations). 3D models of the identified tumor voxel cluster, including (a) all identified voxels and (b) those showing the highest t-values.
