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. 2012 Aug 31;1(1):49–70. doi: 10.2217/cns.12.5

Table 4. . Response rate and 6-month progression-free survival in pooled analyses of trials for recurrent GB.

Publication Sample size Response rate (%) PFS6 (%) OS (months) 1-year survival (%) Ref.
8 MD Anderson trials 1986–1995 225 6 15 5.7 21 [23]

16 NCCTG trials 345 N/A 9 5.1 14 [24]

12 NABTC trials 437 7 16 6.9 25 [25]

N/A: Not applicable, NABTC: North American Brain Tumor Coalition; NCCTG: North Central Cancer Treatment Group; OS: Overall survival; PFS6: 6-month progression-free survival.