Table 2. Bivariable comparisons between 5hmC and clinico-pathological features.
| 5hmC score | |||||||
|---|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | 4 | |||
| AJCC stage | IA | 4 | 6 | 16 | 18 | 19 | |
| IB | 12 | 22 | 20 | 12 | 5 | ||
| IIA | 6 | 6 | 4 | 2 | 1 | ||
| IIB | 0 | 5 | 9 | 1 | 0 | ||
| IIC | 15 | 9 | 5 | 3 | 0 | p = 0.001 | |
| Age | Mean Years | 64 | 63 | 67 | 53 | 53 | p = 5.34x10-5 |
| Gender | Male | 19 | 24 | 28 | 15 | 15 | |
| Female | 18 | 24 | 26 | 21 | 10 | p = 0.72 | |
| Site | Upper limb | 8 | 8 | 3 | 2 | 3 | |
| Lower limb | 10 | 10 | 17 | 15 | 0 | ||
| Trunk | 6 | 15 | 22 | 9 | 15 | ||
| Head & neck | 8 | 11 | 8 | 9 | 6 | ||
| Acral | 5 | 4 | 4 | 1 | 1 | p = 0.006 | |
| Breslow depth | Mean mm | 6.3 | 2.8 | 2.5 | 1.8 | 0.7 | p = 7.03x10-8 |
| Mitotic rate | Mean per mm2 | 8.8 | 6.0 | 4.1 | 1.6 | 0.4 | p = 3.11x10-9 |
| Ulcer | Absent | 21 | 34 | 43 | 32 | 24 | |
| Present | 16 | 14 | 11 | 4 | 1 | p = 0.0014 | |
| Microsatellites | Absent | 34 | 47 | 52 | 36 | 25 | |
| Present | 3 | 1 | 2 | 0 | 0 | p = 0.26 | |