Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Increased Hh signaling activity in the Enpp1−/− embryo. (A-D) Expression of Hh signaling targets Gli1 (A,B) and Hhip (C,D) in E15.5 WT and Enpp1−/− forelimbs shown, by WISH. Gli1 and Hhip mRNA levels were upregulated in the limbs of the Enpp1−/− embryos. (E-F) qRT-PCR analysis of Hh target gene expression in the forelimbs of E15.5 embryos (n=3). *P<0.05, **P<0.01 (Student's t-test).
