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Overexpression of strumpellin results in an increase of cells with additional nuclei. (A) DAPI staining of nuclei in AX2, AX2|GFP, AX2|StrWT-GFP, AX2|StrN471D-GFP cells. Cells with two or more nuclei are marked by white arrows. Scale bar: 20 µm. (B) Quantification of cells with two or more nuclei. Significance was calculated using Fisher's exact test, followed by Fisher's exact test with Bonferroni correction for post hoc analyses. NS, not significant; **P≤0.01.
