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. 2018 May 9;2(2):yty062. doi: 10.1093/ehjcr/yty062
Day Events
1 Patient experiences syncope after sexual activity on reaching orgasm. After tapping her face, consciousness was recovered within seconds, and she was transferred to our Cardiology unit by the emergency services
Physical examination and laboratory investigations revealed no abnormalities
Baseline 12 lead electrocardiogram revealed a wide based T-wave with a prolonged QT interval of 520 ms with a heart rate of 56 b.p.m.
3 Patient became tachypneuic, dizzy and was unresponsive for a few seconds. Runs of torsades de pointes were recorded simultaneously on telemetry
Magnesium was administered intravenously
A beta-blocker (metoprolol) was started
8 Patient was treated with an implantable cardioverter-defibrillator
35 Genetic testing revealed a mutation in the KCNH2 gene encoding the alpha-subunit of the delayed rectifier potassium channel