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| Compounda | HDAC1 | HDAC2 | HDAC4 | HDAC6 | HDAC10 |
|---|---|---|---|---|---|
| 3d | 5,26E-08 | 9,33E-08 | n.a | 1,56E-09 | 2,24E-07 |
| 3b | 4,30E-08 | 7,62E-08 | n.a. | 3,87E-09 | 9,99E-08 |
| Trichostatin A | 1,244E-08 | 2,36E-08 | - | 2,09E-09 | 3,20E-08 |
| TMP269 | -- | -- | 3.53E-07 | -- | -- |
aIC50 values were calculated using the GraphPad Prism 4 program based on a sigmoidal dose-response equation.
n.a. = not active. Trichostatin A and TMP269 were used as reference standards
