Table 1. Demographic and structural and angiography optical coherence tomography characteristics by group.
| Group 1 (Active nAMD) | Group 2 (Remission nAMD) | p-value* | |
|---|---|---|---|
| Age (years) | 81.1 (7.6) | 81.1 (7.0) | 0.963 |
| Disease duration (months) | 52.8 (33.6) [8, 125] | 189.8 (82.1) [36, 358] | <0.001 |
| Number of IVI | 17.0 (11.0–27.3) [5, 69] | 12.0 (9.0–14.3) [5, 27] | 0.003 |
| VA (ETDRS letters) | 65.0 (49.0–75.0) [13.0, 89.0] | 44.0 (31.0–55.0) [3.0, 83.0] | <0.001 |
| FD | 1.44 (0.09) [1.24, 1.66] | 1.50 (0.04) [1.40, 1.58] | <0.001 |
| LAC | 0.38 (0.06) [0.27, 0.53] | 0.39 (0.36–0.42) [0.32, 0.47] | 0.195 |
| Area (mm2) | 1.94 (0.76–3.30) [0.12, 13.03] | 5.82 (3.72–8.20) [1.17, 12.82] | <0.001 |
| Density (%) | 0.49 (0.41–0.56) [0.26, 0.87] | 0.39 (0.36–0.45) [0.26, 0.60] | <0.001 |
| Aspect ratio | 0.70 (0.13) [0.40, 0.93] | 0.74 (0.14) [0.46, 0.94] | 0.093 |
| CMT (μm) | 301.5 (257.8–372.3) [185.0, 854.0] | 260.0 (214.8–308.5) [130.0, 451.0] | <0.001 |
Continuous variables were presented as mean and standard deviation (SD) or median and interquartile range (25th percentile - 75th percentile) and range ([min, max]), as appropriate. IVI: Intra vitreal injection–. FD—Fractal dimension. LAC–Lacunarity. nAMD: neovascular Age Related Macular Degeneration. CMT—Central Macular Thickness. VA–Visual Acuity.
*Obtained by chi-squared and Mann–Whitney non parametric tests.