Table 1. Characteristics of the studies included in the meta-analysis.
| Study | Yr | Ref # | Country | Setting | Diagnostic criteria | Genotyping | DHF cases/ Healthy controls |
Age group | Study quality score | Cases | Controls | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A/G | AA/GA/GG | A/G | AA/GA/GG | ||||||||||
| Perez | 2010 | 25 | Cuba | population based | 1997 WHO criteria | PCR-SSP | 43/99 | adults | 7 | 29/57 | 9/11/23 | 21/145 | 14/7/69 |
| García-Trejo | 2011 | 26 | Mexico | hospital based; | 1997 WHO criteria | PCR-RFLP | 45/169 | adults | 7 | 0/64 | 0/0/32 | 23/315 | 1/21/147 |
| Xavier-Carvalho | 2013 | 27 | Brazil | hospital based; | 2009 WHO/TDR | Real-time PCR | 88/335 | children | 8 | 20/144 | 2/16/64 | 73/585 | 6/66/271 |
| Alagarasu | 2015 | 28 | India | hospital based | 1999 WHO criteria | ARMS-PCR | 45/108 | adults | 8 | 6/84 | 0/6/39 | 13/203 | 0/13/95 |
| Fernando | 2015 | 29 | Sri Lanka | hospital based | 2011 WHO criteria | ARMS-PCR | 107/52 | adults | 5 | 14/200 | 2/10/95 | 28/107 | 2/13/47 |
| Sam | 2015 | 30 | Malaysia | hospital based | 1997 WHO criteria | PCR-RFLP | 196/120 | Mostly adults | 8 | 17/373 | 0/17/178 | 24/216 | 1/22/97 |
| dos Santos | 2017 | 31 | Brazil | hospital based | 1997 WHO criteria | Real-time PCR | 49/135 | adults | 7 | 10/88 | 0/10/39 | 39/231 | 3/33/99 |
| Sanchez-Leyva | 2017 | 32 | Mexico | hospital based | 1997 WHO criteria | PCR-RFLP | 67/257 | adults | 9 | 12/122 | 3/6/58 | 35/497 | 2/31/224 |