. Author manuscript; available in PMC: 2019 Oct 28.

Published in final edited form as: J Control Release. 2018 Sep 14;288:212–226. doi: 10.1016/j.jconrel.2018.09.011

Table 2.

Physicochemical Characterizations of DOX-loaded and PTX-loaded POEG-b-PPPMP Micelles.

Micelles	Mass ratio (mg: mg) ^a	Size (nm) ^b	PDI ^c	DLC (%) ^d	DLE (%) ^e	Stability ^f (RT)	Stability ^f (4°C)

POEG₁₅-b-PPPMP₇		105.0	0.179
POEG₁₅-b-PPPMP₇ : DOX	10:1	87.58	0.221	6.5	68.9	48 h	6 d
POEG₁₅-b-PPPMP₇ : DOX	20:1	82.46	0.214	3.8	79.7	4 d	25 d
POEG₁₅-b-PPPMP₇ : DOX	30:1	79.77	0.196	2.8	86.7	7 d	37 d
POEG₁₅-b-PPPMP₇ : DOX	50:1	89.34	0.193	1.9	96.0	12 d	42 d
POEG₁₅-b-PPPMP₇ : PTX	10: 1	107.1	0.205	8.2	90.4	24 h	51 h
POEG₁₅-b-PPPMP₇ : PTX	20: 1	97.7	0.212	4.4	92.5	45 h	6 d
POEG₁₅-b-PPPMP₇ : PTX	30: 1	95.8	0.217	3.1	95.2	53 h	17 d
POEG₁₅-b-PPPMP₇ : PTX	50:1	93.2	0.205	1.9	95.6	7 d	21 d

^a)

DOX or PTX concentration in micelles was kept at 0.5 or 1 mg/mL respectively.

^b)

Measured by dynamic light scattering particle sizer.

^c)

PDI = polydispersity index.

^d)

DLC = drug loading capacity.

^e)

DLE = drug loading efficiency.

^f)

Data mean there was no noticeable size change and visible precipitates during the follow-up period.