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Pharmacokinetic Parameters of DOX in Different Formulations.
| Groups | T1/2(h) | AUC0−∞ (μg/ml*h) | Cmax (μg/µL) | CL (µL/h) | Vd (µL) |
|---|---|---|---|---|---|
| DOX.HCl | 3.35 | 9.20 | 4.41 | 10.87 | 52.49 |
| POEG-b-POM/DOX | 15.96 | 84.31 | 21.30 | 1.19 | 27.31 |
| POEG-b PPPMP/DOX | 16.19 | 180.16 | 27.60 | 0.56 | 12.97 |
