Table 4.
Association between TICs of biochemical markers and changes in MRI features over 12 and 24 months.
| Biochemical marker | MRI markers | ||||
|---|---|---|---|---|---|
| Hoffa-synovitis | Effusion-synovitis | ||||
| Improvement/No change | Worsening | Improvement | No change | Worsening | |
| 12 months | |||||
| sHA | REF | 0.85 (0.54, 1.33) | 0.92 (0.71, 1.21) | REF | 0.82 (0.61, 1.11) |
| sMMP-3 | REF | 0.79 (0.44, 1.39) | 0.85 (0.59, 1.22) | REF | 0.88 (0.65, 1.18) |
| sColl2–1NO2 | REF | 0.85 (0.51, 1.41) | 0.81 (0.55, 1.29) | REF | 1.04 (0.85, 1.26) |
| 24 months | |||||
| sHA | REF | 1.03 (0.78, 1.35) | 1.01 (0.80, 1.26) | REF | 1.01 (0.78, 1.31) |
| sMMP-3 | REF | 0.92 (0.62, 1.36) | 0.87 (0.59, 1.27) | REF | 0.84 (0.63, 1.10) |
| sColl2–1NO2 | REF | 1.07 (0.87, 1.36) | 0.97 (0.68, 1.38) | REF | 1.17 (0.96, 1.42) |
Adjusted for age, gender, BMI, baseline KLG and respective baseline feature on MRI. Odds ratio and 95% confidence intervals (CI) are presented in the table.