Table 1.
Critical O2 tension (mmHg) | Function or parameter observed |
---|---|
30–35 | Effectiveness of certain (passive) immunotherapies |
15–35 | Cell death with PDT |
25–30 | Cell death on exposure to χ- and γ-radiation |
10–20 | Binding of hypoxia markers |
1–15 | Proteome changes |
0.2–1 | Genome changes |
Note:
Reformatted from Höckel M, Vaupel P, Tumor hypoxia: definitions and current clinical, biologic, and Molecular Aspects. J Natl Cancer Inst. 2001;93(4):266–276, by permission of Oxford University Press.15
Abbreviation: PDT, photodynamic therapy.