Figure 7.

In vivo antitumor activity (n=4).

Notes: (A) Relative tumor volume after different treatments. (B) Representative photographs of the tumors collected from various groups of mice at the end of the treatment (day 21). (C) The tumor weights at the end of therapy on day 21. (D) The body weight of mice during treatment. *P<0.05, **P<0.01, and ***P<0.001. (E) In vivo fluorescence images of HeLa tumor-bearing nude mice treated with HA-HMCN(DOX)@GQDs under laser irradiation at different time points.

Abbreviations: DOX, doxorubicin; GQDs, graphene quantum dots; HA, hyaluronic acid; HMCN, hollow mesoporous carbon nanoparticle.