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. 2018 Oct 4;10:4191–4202. doi: 10.2147/CMAR.S178219

Figure 3.

Figure 3

Knockdown of PKM2 inhibited proliferation in CC cells.

Notes: (A, B) PKM2 knockdown efficiency was confirmed by Western blot and qRT-PCR in HeLa and SiHa cells. (C, D) The effects of PKM2 knockdown on proliferation were evaluated using CCK-8 assay. (E, F) The effects of PKM2 knockdown on colony formation were determined using colony formation assay. The results shown are the mean ± SD (*P<0.05, **P<0.01) of three independent experiments.

Abbreviations: CC, cervical cancer; PKM2, pyruvate kinase isozyme type M2; qRT-PCR, quantitative real-time polymerase chain reaction.