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. 2018 Oct 4;10:4237–4248. doi: 10.2147/CMAR.S162383

Figure 6.

Figure 6

Capsaicin induced apoptosis through upregulating TRIB3 expression in cancer cells.

Notes: The proposed model is consistent with the published studies and the results described here. Capsaicin dose- and time-dependently induces TRIB3 expression via both stimulating gene transcription and stabilizing protein stability mechanisms to promote apoptosis in cancer cells.

Abbreviation: CHX, cycloheximide.