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. 2017 Dec 11;175(21):4083–4094. doi: 10.1111/bph.14086

Figure 2.

Figure 2

Structure of synthetic calcimimetic and calcilytic compounds. (A) Synthetic type II calcimimetics comprise a structurally diverse group of compounds, which include phenylalkylamines such as NPS R‐568 and cinacalcet; AC265347, which has a benzothiazole structure; and etelcalcetide, which is a polycationic peptide. (B) All calcilytics described to date are synthetic compounds and are divided into two classes: amino alcohols such as NPS 2143, ronacaleret, NPSP795 and JTT‐305/MK‐5442 and the quinazolinone‐derived calcilytics such as AXT 914 and ATF 936.