Table 1.
Patients’ characteristics
| Demographics | |
|---|---|
| Gender, no. (%) | Male: 201 (59.8) |
| Female: 135 (40.2) | |
| Age (years), median (range) | 69 (26–90) |
| Weight (kg), median (range) | 61 (37–130) |
| Medical and disease history | |
|---|---|
| Premedication, no. (%) | No: 221 (65.8) |
| Yes: 115 (34.2) | |
| Hypertension, no. (%) | No: 110 (32.7) |
| Yes: 226 (67.3) | |
| Previous stroke, no. (%) | No: 261 (77.7) |
| Yes: 75 (22.3) | |
| Diabetes, no. (%) | No: 248 (73.8) |
| Yes: 88 (26.2) | |
| Cardiovascular diseases, no. (%) | No: 146 (43.5) |
| Yes: 190 (56.5) | |
| (1:130, 2:47, 3:11, 4:2)a | |
| Baseline status | |
|---|---|
| NIHSS score, median (range) | 14 (2–36) |
| Location of infarction, no. (%) | MCA: 246 (73.2) |
| PCA: 12 (3.6) | |
| Basilar: 18 (5.4) | |
| Multiple: 33 (9.8) | |
| Others: 27 (8.0) | |
| Creatinine (mg dl –1 ), median (range) | 0.95 (0.4–14.9) |
| Platelet count (× 10 3 μl), median (range) | 233 (107–568) |
| Glucose (mg dl –1 ), median (range) | 124.5 (67–580) |
| INR, median (range) | 0.97 (0.78–3.32) |
| Systolic blood pressure (mmHg), median (range) | 150 (93–270) |
| Diastolic blood pressure (mmHg), median (range) | 81 (46–210) |
| Treatment factors | |
|---|---|
| Time to treatment (h), median (range) | 1.63 (0.23–3.82) |
| Dose (mg kg –1 ), median (range) | 0.9 (0.36–1.45) |
| Additional therapy, no. (%) | No: 229 (68.2) |
| Yes: 107 (31.8) | |
| Haemorrhage in rt‐PA treatment only, no. (%) |
No: 192 (83.8) Yes: 37 (16.2) |
INR, international normalized ratio; MCA, middle cerebral artery; NIHSS, National Institutes of Health Stroke Scale; PCA, posterior cerebral artery; rt‐PA, recombinant tissue plasminogen activator
a
In A:B, A means the number of cardiovascular diseases each patient had and B the number of patients