Figure 1.

Beeswarm plot of the distribution of posaconazole trough concentrations (n = 176) following administration of posaconazole tablets in hematologic patients, in relation to week of treatment. Solid lines identify median and 25th–75th percentiles within each group. The dashed line identifies posaconazole target level for prophylaxis (C _min > 0.7 mg l⁻¹) of fungal infections. A P‐value = 0.005 was obtained at Kruskal–Wallis test. A significant difference after post‐hoc Bonferroni correction was observed between week 1 and week 4 (P = 0.007) and week 1 and week >4 (P < 0.001)