Table 1.
Demographic and clinical characteristics of the patient group (n = 300)
| Characteristic | Value |
|---|---|
| Age (years), mean (SD) | 65.0 (9.3) |
| Male sex, n (%) | 179 (59.7) |
| History of smoking | |
| Current smoker, n (%) | 71 (23.7) |
| Nonsmoker, n (%) | 214 (71.3) |
| Ex‐smoker, n (%) | 15 (5.0) |
| Positive family history of premature cardiovascular disease, n (%) | 52 (17.3) |
| BMI (kg m –2 ), mean (SD) | 29.1 (4.7) |
| TMAO (μmol l –1 ) median (IQR) | 2.144 (1.570–3.104) |
| log‐TMAO, mean (SD) | 0.347 (0.277) |
| eGFR creat (ml min –1 1.73‐m –2 ), mean (SD) | 81.58 (16.48) |
| eGFR creat categories | |
| G1, n (%) | 102 (34.0) |
| G2, n (%) | 160 (53.3) |
| G3a, n (%) | 32 (10.7) |
| G3b, n (%) | 5 (1.7) |
| G4, n (%) | 1 (0.3) |
| G5, n (%) | 0 (0) |
| Cholesterol (mmol l –1 ), mean (SD) | 4.37 (1.19) |
| Triglycerides (mmol l –1 ), median (IQR) | 1.01 (1.00–1.90) |
| HDL‐C (mmol l –1 ), mean (SD) | 1.22 (0.41) |
| LDL‐C (mmol l –1 ), mean (SD) | 2.54 (1.00) |
| ALT (U l –1 ), mean (SD) | 30.19 (20.76) |
| Conjugated bilirubin (U l –1 ) mean (SD) | 4.82 (3.12) |
| Unconjugated bilirubin (U l –1 ), mean (SD) | 7.93 (4.35) |
| CK (U l –1 ), mean (SD) | 131.07 (90.81) |
ALT, alanine aminotransferase; BMI, body mass index; CK, creatine kinase; eGFRcreat, estimated glomerular filtration rate based on 2009 CKD‐EPI creatinine equation; HDL‐C, high‐density lipoprotein cholesterol; IQR, interquartile range; LDL‐C, low‐density lipoprotein cholesterol; SD, standard deviation; TMAO, trimethylamine‐N‐oxide