Fig. 2.

Bladder cancer cell-derived exosomes enhance the proliferation and migration of cultured lymphatic endothelial cells (LECs). Conditioned medium was harvested from cultured T24 bladder cancer cells (American Type Culture Collection, ATCC) and subjected to the ultracentrifugation process to isolate tumor-secreted exosomes. Human dermal LECs (ATCC) were treated with the isolated exosomes or phosphate buffered saline (PBS) (control). Migration (A) and proliferation (B) was compared between PBS-treated LECs and exosome-treated LECs. *P<0.05.