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. 2018 Sep 6;11(4):1009–1020. doi: 10.1016/j.stemcr.2018.08.007

Table 1.

Duration of Cultures Used for Mast Cell Generation from Different Cell/Tissue Sources

Source Culture Time Reference
hPB 8–12 weeks Kirshenbaum and Metcalfe, 2006, Saito et al., 2006, Wang et al., 2006
hCB 12 weeks Holm et al., 2006
hBM 12 weeks Shimizu et al., 2002
mESC 4–8 weeks Moller et al., 2007, Tsai et al., 2002, Westerberg et al., 2012
miPSC 4 weeks Yamaguchi et al., 2013
hESC 10 weeks Kovarova et al., 2010
hiPSC 5 weeks Igarashi et al., 2018
G2V mESC 14–21 days this study
G2V hESC/iPSC 12–16 days this study

Duration (weeks/days) of cultures for human (h) mast cell generation from progenitors isolated from primary tissue sources such as peripheral blood (hPB), cord blood (hCB), and bone marrow (hBM); from wild-type and Gata2Venus (G2V) reporter mouse embryonic stem cells (mESC); and human ESCs (hESC) and induced pluripotent stem cells (iPSC). References for each of the studies are indicated.