Table 6.
Univariate and multivariate regression analysis for predictive factors of major morbidity occurrence following CRS and HIPEC in our patients.
| Univariate Analysis |
Multivariate Analysis |
|||
|---|---|---|---|---|
| Hazard Ratio [CI] | P | Hazard Ratio [CI] | P | |
| Age | 1.852 [1.192–3.017] | 0.040 | 1.635 [0.829–3.657] | 0.119 |
| Sex | 0.917 [0.643–1.381] | 0.938 | NS | NS |
| Charlson score ≥1 | 2.897 [1.936–4.537] | 0.011 | 2.013 [1.286–3.168] | 0.044 |
| PCI | 0.739 [0.197–2.528] | 0.639 | NS | NS |
| CC-0/1 | 0.532 [0.099–3.264] | 0.939 | NS | NS |
| Postoperative fluids | 0.714 [0.163–1.685] | 0.761 | NS | NS |
| Postoperative AKI | 2.774 [1.653–6.313] | 0.002 | 1.855 [1.226–2.431] | 0.030 |
Numbers in bold: statistically significant.
AKI = Acute Kidney Injury, CC = Completeness of Cytoreduction, CRS = Cytoreductive Surgery, HIPEC = Hyperthermic Intraperitoneal Chemotherapy, PCI = Peritoneal Carcinomatosis Index.