Table 2. Selected PET radiotracers used for prostate cancer imaging.

PET radiotracers	Mechanism of action
[18F]FDG	Glucose metabolism
Na[18F]F	Bone chemisorption
[18F]choline, [11C]choline	Cell membrane metabolism
[18F]DCFPyl, [68Ga]PSMA-11	PSMA binding
[11C]acetate	Fatty acid metabolism
[18F]fluciclovine	Amino acid transport
[68Ga]DOTA-bombesin	GRPR receptor binding
[18F]FDHT	Androgen receptor binding

Reproduced with permission from the World Journal of Radiology article Zarzour JG et al. Lymph node imaging in initial staging of prostate cancer: an overview and update. PET, positron emission tomography; [¹⁸F]FDG, [¹⁸F]fluoro-D-glucose; [¹⁸F]NaF, sodium [¹⁸F]fluoride; [¹⁸F] DCFPyl, [¹⁸F] 2-(3-(1-carboxy-5-[(6-[¹⁸F]fluoro-pyridine-3-carbonyl)-amino]-pentyl)-ureido)-pentanedioic acid; [¹⁸F]FDHT, [¹⁸F]fluorodehydrotestosterone; GRPR, gastrin-releasing peptide receptor.