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. 2018 Oct 9;9(10):1031. doi: 10.1038/s41419-018-1098-4

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Representative staining for α-SMA and synaptopodin as quantified in (b), staining for collagen 1α (Col1α) and synaptopodin as quantified in (c) and staining for fibronectin as quantified in (d). Scale bars represent 10 or 25 μm as shown in the photos. White arrows showed the positive podocytes for EMT markers. e Representative images of western blot for EMT markers in glomeruli. f–h Apelin inhibited the increased expression of α-SMA, fibronectin, and collagen 1α in glomeruli of kkAy mice. Values represent the mean ± SD (n = 6 mice per group, *p < 0.05 **p < 0.01)