Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Oct 9;8:14999. doi: 10.1038/s41598-018-33403-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Mitochondrial dysfunction and apoptosis in platelets from HIV-infected individuals under stable cART. (A) The mean fluorescence intensity (MFI) for TMRE indicating the mitochondrial membrane potential (∆ψ_m), (B) the MFI for MitoSoxRed indicating mitochondrial generation of reactive oxygen species (ROS_m), (C) the percentage of platelets that bind annexin V, and (D) the MFI for the probe FLICA indicating caspase-9 activation were assessed in platelets freshly-isolated from healthy volunteers (control) or from HIV-infected individuals under viral control (HIV-1 viral load < 50 copies/ml in the peripheral blood). Box plots: The horizontal lines on the box plots represent the median, boxes limits indicate interquartile ranges and the whiskers indicate 5–95 percentile. The asterisk (*) signify p < 0.05 compared to healthy volunteers.