Fig. 3.

Different metastatic ACC sites within the same patient are predominantly homogenous. Heatmap and clustering of the total number of overlapping and non-overlapping variants within the genes that are mutated in multiple tumor sites from each patient (a–d). The list of genes with shared mutations between lung and other tissue in the hypermutated patient (d) were shown in a box. Red bar in the heatmap indicates the gene is mutated, whereas the blue represents that the corresponding gene is wild-type in each sample