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. 2018 Aug 12;2(4):790–799. doi: 10.1002/rth2.12141

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© 2018 The Authors. Research and Practice in Thrombosis and Haemostasis published by Wiley Periodicals, Inc on behalf of International Society on Thrombosis and Haemostasis.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Rationalization of patient results according to the VWF activity, VWF Ac, ratio of VWF Ac/VWF:antigen (VWF:Ag) and in‐house multimer, IHVWM, result. Patients were group according to VWF Ac and then ratio of VWF activity and VWF:Ag. IHVWM pattern was assessed as normal or reduced high molecular weight multimers (HMWM) when less than 11 multimer triplets were visible. The number of patients with discrepancy between IHVWM and Hydragel 5 multimer method, H5VWM, is indicated. Results from patients with type 2N, type 3 and acquired von Willebrand syndrome (AVWS) were excluded