TABLE 2.
Activities of AX-35 and AX-36 against selected microorganisms
| Microorganism | MIC (µg/ml) of: |
||
|---|---|---|---|
| AX-35 | AX-36 | RIF | |
| Bacillus subtilis | >100 | >100 | 0.3 |
| Candida albicans | >100 | >100 | 1.5 |
| Corynebacterium diphtheriae | >100 | >100 | 0.0004 |
| Corynebacterium glutamicum | >100 | >100 | 0.004 |
| Enterococcus faecalis | >100 | >100 | 0.6 |
| Escherichia coli | 74 | 100 | 6.7 |
| Listeria monocytogenes | >100 | >100 | 0.8 |
| Micrococcus luteus | >100 | >100 | 0.7 |
| Mycobacterium avium | 8.2 | 12.8 | 25 |
| Mycobacterium bovis BCG | 0.8 | 0.8 | 0.0008 |
| Mycobacterium canettii STB-L | 0.003 | 0.01 | 0.002 |
| Mycobacterium marinum | 11.5 | 19.6 | 0.5 |
| Mycobacterium massiliense | 7.7 | 10.4 | 26.9 |
| Mycobacterium smegmatis | 100 | 63 | 1.7 |
| Mycobacterium tuberculosis | 0.05 | 0.1 | 0.001 |
| Mycobacterium ulcerans | 1.6 | 1.6 | 0.01 |
| Mycobacterium vaccae | 12.1 | 26.9 | 2.5 |
| Pseudomonas aeruginosa | >100 | >100 | 1 |
| Pseudomonas putida | >100 | >100 | 0.2 |
| Salmonella enterica serovar Typhimurium | >100 | >100 | 0.7 |
| Staphylococcus aureus | >100 | >100 | 3.8 |