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. 2015 Dec 30;3(2):116–124. doi: 10.1002/mdc3.12266

Table 3.

Binding profile of clozapine on various pharmacological receptors, compared to quetiapine and the anticholinerigcs, trihexyphenydyl and benztropine

Receptor Ki Clozapinea Ki Quetiapinea Ki Trihexyphenidyl Ki Benztropine
5‐HT2A 13 366
5‐HT2B 7.15b
5‐HT2C 29 1,500
5‐HT1A 105 431
M1 14 858
M4 29 542 2.6c 1.1a , c
H1 2 7.5
α1 6.8d 8.1d
α2 15d 80d
D2 431 567
D4 39 1,202
a

Reference number 9.

b

Reference number 29.

c

Reference number 30.

d

Reference number 65.