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. Author manuscript; available in PMC: 2019 Jun 8.
Published in final edited form as: Dement Geriatr Cogn Disord. 2018 Jun 8;45(3-4):232–242. doi: 10.1159/000488671

Figure 1: Change in cognition over time for participants with sleep disturbance (PSD) and without sleep disturbance (NSD).

Figure 1:

Memory (ADNI-Mem), executive function (ADNI-EF), and global cognitive (ADAS-11) performance over time for PSD and NSD groups stratified by baseline diagnosis of cognitively normal (CN), early MCI (EMCI), late MCI (LMCI), or AD-dementia (AD). Repeated measures linear mixed models were used to compare the effect of sleep group (NSD or PSD) on change in cognitive outcome over time. The model was adjusted for age, sex, APOE genotype, education level, and sedative/hypnotic use. The confidence level for statistical inference was 95% (p < 0.05). Plotted values are mean with error bars for standard error of the mean. FDR correction was performed for multiple comparisons.