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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Drug Alcohol Depend. 2018 Aug 25;191:343–347. doi: 10.1016/j.drugalcdep.2018.07.013

Fig. 1.

Fig. 1.

Enriched environment (EE) led to behavioral phenotypes associated with lower drug addiction risk in rats with or without prenatal ethanol exposure (PE). (A) Rats reared in EE exhibited lower locomotor responding to novelty than rats reared in the impoverished environment (IE), regardless of prenatal treatments (control or PE). The left panel depicts photo beam breaks within 5-min epochs. The right panel is a summary plot for total photo beam breaks in 1 h. (B) Rats reared in EE showed lower anxiety than rats reared in IE, demonstrated by longer open arm stay/travel time (percentages within 5 min) in an elevated plus maze test, regardless of prenatal treatments (control or PE). Data are presented as Mean ± SEM. ***: p < 0.001, IE vs. EE rats in either the control or PE group, planned comparisons after ANOVA.