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. Author manuscript; available in PMC: 2018 Oct 10.
Published in final edited form as: ACS Biomater Sci Eng. 2017 May 15;3(6):1017–1026. doi: 10.1021/acsbiomaterials.7b00039

Table 1.

NO-Release Properties of Ester-Modified Chitosan Oligosaccharides PBS (pH 6.5, 37 °C)a

[NO]totalb (μmol/mg) [NO]maxc (ppb/mg) t(l/2)d (min) tde (h)
COS-NO 0.44 ± 0.11 2800 ± 600 36.1 ± 2.8 7.85 ± 0.75
COS-EA-NO 0.42 ± 0.16 3200 ± 1100 28.8 ± 5.2 7.62 ± 0.67
COS-TBuA-NO 0.42 ± 0.09 2500 ± 400 25.3 ± 8.6 7.74 ± 0.74
COS-SPA-NO 0.39 ± 0.12 3300 ± 1100 28.9 ± 4.3 6.72 ± 1.92
a

All values are reported as the mean ± standard deviation for 3 or more pooled experiments.

b

Total NO.

c

Max NO Flux.

d

Half-life.

e

Duration of NO-release.