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Treatment with LDL and IL-1β activates the NLRP3 inflammasome in MPC5 cells via CD36. MPC5 cells were treated as indicated. Protein expression of NLRP3 (A) and caspase-1 activity (B) were determined by Western blotting and using a commercial kit, respectively. *, *** p<0.05 vs. CTR cells; **, **** p<0.05 vs. LDL+IL-1β-treated cells.
