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. 2018 Oct 3;5:232. doi: 10.3389/fvets.2018.00232

Table 2.

Estimated relative and absolute potencies (IU/mg) of pairs of tuberculin batches with 95% CI's in six guinea pig trials.

Trial Batch pair N Rel. pot. (95% CI) Potency (95% CI)
T1 RS, BIS 48 1.230 (0.757–2.025) 39,975 (24,603–65,813)*
A, BIS 48 1.233 (0.828–1.853) 40,073 (26,910–62,223)*
A, RS 48 1.095 (0.739–1.627) 37,997 (25,643–56,457)**
T2 RS, BIS 48 Non-parallel
A, BIS 48 Significant curvature
A, RS 48 Non-parallel
T3 RS, BIS 45 Non-parallel
A, BIS 45 0.782 (0.444–1.338) 25,415 (14,430–43,485)*
A, RS 46 1.081 (0.760–1.542) 35,133 (24,700–50,115)**
T4 RS, BIS 41 1.132 (0.678–1.893) 39,280 (23,527–65,687)*
C, BIS 43 1.103 (0.710–1.689) 35,848 (23,075–54,893)*
C, RS 44 0.957 (0.639–1.417) 33,208 (22,173–49,170)**
T5 RS, BIS 39 0.954 (0.585–1.565) 31,005 (19,013–50,863)*
D, BIS 42 1.181 (0.794–1.756) 38,383 (25,805–57,070)*
D, RS 41 1.189 (0.766–1.827) 41,258 (26,580–63,397)**
T6 RS, BIS 41 1.131 (0.745–1.761) 36,785 (24,213–57,233)*
B, BIS 42 0.975 (0.656–1.465) 31,688 (21,320–47,613)*
B, RS 39 0.852 (0.559–1.285) 29,564 (19,397–44,590)**
T1, T4, T5, T6 RS, BIS 169 1.115 (0.871–1.432) 36,238 (28,308–46,540)*
*

Relative potencies multiplied by 32,500 (potency assigned to BIS).

**

Relative potencies multiplied by 34,700 (potency assigned to RS when calibrated against bis in cattle).