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. 2018 Oct 5;11:6569–6577. doi: 10.2147/OTT.S167187

Figure 4.

Figure 4

Effects of IGFBP3-specific siRNA on Bcl-2, Bax, and active caspase-3 expression levels in A431 cells.

Notes: Representative Western blot images and summary data showing Bcl-2 (A, B), Bax (A, C), and active caspase-3 (A, D) protein expression levels in A431 cells transfected with scrambled or IGFBP3-specific siRNA. The OD of each protein was normalized to β-tubulin. Values shown are the mean ± SEM (n = 3–4). *P < 0.05 for scrambled siRNA vs IGFBP3-specific siRNA.

Abbreviations: Bcl-2, B-cell lymphoma-2; IGFBP3, insulin-like growth factor binding protein-3; SEM, standard error of the mean.