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. Author manuscript; available in PMC: 2018 Oct 10.
Published in final edited form as: Curr Opin Genet Dev. 2011 Aug 19;21(6):719–725. doi: 10.1016/j.gde.2011.07.009

Figure 2.

Figure 2

Model for the regulation of the expression pattern of broad (br). (a, e) The EGFR pathway regulates br in an incoherent feedforward loop, where EGFR activation induces both br (at a low threshold value θ2) and its repressor R (at a higher threshold value θ2). (b) BR (red) is expressed in two groups of follicle cells (nuclei shown in blue) on either side of the dorsal midline, (c–f) Mathematical model for the two-dimensional distribution of GRK and BR expression. Arrow heads mark the position of the dorsal midline.