Table 1.
Accuracy is measured as the ratio of recovered to true radiotracer concentration or parameter value. APPIAN accurately recovers radiotracer concentrations and tracer kinetic parameters from the SORTEO simulated PET images.
| Radiotracer | ROI | PVE | Analysis | Metric | Accuracy |
|---|---|---|---|---|---|
| FDG | GM | Uncorrected | Coregistration | integral | 0.66 ± 0.006 |
| FDG | GM | Corrected | PVC | integral | 0.93 ± 0.025 |
| FDG | GM | Corrected | Quantification | SUVR | 0.94 ± 0.048 |
| FDOPA | Putamen | Uncorrected | Coregistration | integral | 0.69 ± 0.03 |
| FDOPA | Putamen | Corrected | PVC | integral | 1 ± 0.055 |
| FDOPA | Putamen | Corrected | Quantification | Ki | 0.83 ± 0.238 |
| RCL | Caudate Nucleus | Uncorrected | Coregistration | integral | 0.77 ± 0.016 |
| RCL | Caudate Nucleus | Corrected | PVC | integral | 1.05 ± 0.035 |
| RCL | Caudate Nucleus | Corrected | Quantification | BPnd | 1.03 ± 0.042 |