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. 2018 Oct 10;56(1):422–432. doi: 10.1080/13880209.2018.1495748

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© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 10. — Apoptosis study of MDA-MB-231 cells exposed to MEDL at IC₅₀ value. The distribution of cells undergoing early and late apoptosis together with viable and necrotic cells following treatment with MEDL for 24 h (A) and 48 h (B) in comparison with respective control using Annexin-FITC and PI flow cytometric analysis. The values are presented as mean ± standard error of mean of three determinations, and where indicated by: (A) showed a significant difference (p < 0.05) relative to the untreated cell; (B) showed a significant difference (p < 0.05) relative to the 5-FU-treated cell.