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. 2018 Oct 4;33(1):1529–1536. doi: 10.1080/14756366.2018.1512598

Table 3.

IC50 of EPO inhibitors in dependence of substituents of functional groups in position 2

Compound Structure IC50 value (µM)
10 (2-[(4-chlorophenyl) amino]- acetohydrazide; PAAH) graphic file with name IENZ_A_1512598_ILG0001.gif 0.021 ± 0.005
11 (2-[(4-chlorophenyl) amino]- acetic acid; PAAA) graphic file with name IENZ_A_1512598_ILG0002.gif 0.205 ± 0.03
12 (2-(4-chlorophenyl) thio-acetohydrazide) graphic file with name IENZ_A_1512598_ILG0003.gif 1.200 ± 0.08
13 (2-(4-chlorophenoxy)-aceto-hydrazide) graphic file with name IENZ_A_1512598_ILG0004.gif 4.900 ± 0.1