Table 3.
Inhibition of C. neoformans ATCC 6895 growth in presence of selected compounds at 37 °C in the aerobic environment or in 5.5% CO2.
Compound (3mM) | Growth inhibition (%) vs. control |
|
---|---|---|
Air | 5.5% CO2 | |
30 | 42.9 ± 26.4**,# | 13.3 ± 12.4 |
12 | 4.2 ± 5.9 | 0.0 ± 0.0 |
ETZ | 25.6 ± 15.6** | 8.2 ± 11.2 |
ETZ: ethoxyzolamide.
p < 0.01 vs. control (medium added with solvent alone).
p < 0.05 vs. compound 30 in 5.5% CO2, assessed by Student’s t test.