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Somatic mutation landscape of ccRCC based on 10 genes that are selected for either prevalent mutations or shown prognostic/therapeutic significances. Top panel represents 220 metastatic ccRCC patients in the reported NGS cohort of RECORD3 [25], and bottom panel represents 418 ccRCC patients of all stages in the reported TCGA KIRC cohort [3]. MTORp denotes MTORC1 pathway.
