Table 1.
Patient Characteristics of Eligible Randomized Patients, By Arm
| ARQ 197 | ARQ 197 + Erlotinib | |||
| (n = 25) | (n = 25) | |||
| AGE | ||||
| Median | 62.1 | 63.6 | ||
| Minimum | 20.3 | 22.8 | ||
| Maximum | 76.1 | 81.9 | ||
| SEX | ||||
| Males | 19 | 76% | 15 | 60% |
| Females | 6 | 24% | 10 | 40% |
| HISPANIC | ||||
| Yes | 1 | 4% | 1 | 4% |
| No | 23 | 92% | 21 | 84% |
| Unknown | 1 | 4% | 3 | 12% |
| RACE | ||||
| White | 19 | 76% | 19 | 76% |
| Black | 6 | 24% | 5 | 20% |
| Unknown | 0 | 0% | 1 | 4% |
| HISTOLOGIC GRADE | ||||
| Unknown | 11 | 44% | 11 | 44% |
| 1 | 0 | 0% | 0 | 0% |
| 2 | 3 | 12% | 5 | 20% |
| 3 | 7 | 28% | 6 | 24% |
| 4 | 4 | 16% | 3 | 12% |
| HISTOLOGIC SUBSET | ||||
| Pure papillary | 20 | 80% | 23 | 92% |
| Mixed histology | 5 | 20% | 2 | 8% |
| HISTOLOGIC TYPE | ||||
| Not Assigned | 12 | 48% | 14 | 56% |
| Type 1 | 2 | 8% | 1 | 4% |
| Type 2 | 11 | 44% | 10 | 40% |
| PRIOR NEPHRECTOMY | ||||
| No | 4 | 16% | 7 | 28% |
| Yes | 21 | 84% | 18 | 72% |
| PRIOR SYSTEMIC THERAPY | ||||
| None | 16 | 64% | 17 | 68% |
| One | 9 | 36% | 8 | 32% |
| PERFORMANCE STATUS | ||||
| 0 | 12 | 48% | 9 | 36% |
| 1 | 11 | 44% | 13 | 52% |
| 2 | 2 | 8% | 3 | 12% |