Table 2.

Frequency of selected pRCC-related mutations among n = 16 out of 35 patient samples in whom adequate tumor tissue DNA was extracted for whole exome sequencing

Gene	N (%)	Chr/exon	Function	AA Change
MET	1 (6)	7 / 18	nsSNV	K1198I
FH	0
CDKN2A	1 (6)	9 /1	Stopgain	P89_delG90
PBRM1	3 (19)	3 / 9,4,17	nsSNV	Y738C
				T113P
				I276V
SETD2	2(12)	3 /12,3	Stopgain	E1991X
			Frameshift deletion	D994fs
KDM6A	2(12)	X / 15,20	Frameshift deletion	L373fs I786fs
FAT1	2(12)	4 / 2,14	nsSNV	S3198F
			Stopgain	Q283X
NF2	1 (6)	22 / 5	Deletion	P123_132del
CUL	1 (6)	2/1	nsSNV	R17P

nsSNV - non-synonymous single nucleotide variant.